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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: β3 Adrenergic Receptor Agonist Mirabegron Increases AQP2 and NKCC2 Urinary Excretion in OAB Patients: A Pleiotropic Effect of Interest for Patients with X-Linked Nephrogenic Diabetes Insipidus
doi: 10.3390/ijms24021136
Figure Lengend Snippet: Localization of β3-AR in the collecting duct, the thick ascending Limb and the proximal tubule in human kidney. Human kidney sections were stained with anti β3-AR antibodies (in red) and co-stained with antibodies against ( A ) AQP2, ( B ) NKCC2 and ( C ) AQP1 (all in green). Overlay shows the expression of β3-AR at the basolateral membrane of cells expressing apical AQP2 (collecting duct), apical NKCC2 (thick ascending limb) but not in the AQP1-expressing tubules (proximal tubule/descending limb). Magnification bar = 25 µm.
Article Snippet: Sections were then incubated with the primary antibodies rabbit anti-BAR3 (SC-50436, Santa Cruz Biotechnology, Inc., www.scbt.com , accessed on 22 November 2022) with
Techniques: Staining, Expressing, Membrane